Harmonization of lipidomics workflows to increase natural lipidome coverage


To promote a community-based survey of lipidomics workflows for identification and quantification of lipids from a variety of natural lipidomes. This includes lipidomes from various species (human, mammalian, invertebrates, algae, plants and bacteria). For animal lipidomes, body fluids (e.g. blood plasma, CSF, saliva), different tissues (e.g. cardiac tissue, liver, adipose tissue), cell types, and exosomes, can be studied.
EpiLipidNET WG1 is working in a close collaboration with International Lipidomics Society and LIPID MAPS consortium.

Expected outcomes

  1. Propose of cartography of lipidomic expertise in Europe
  2. Web-based resource collection of analytical protocols
  3. Promote the establishment of guidelines for sample preparation strategies for different biological matrices
  4. Promote the establishment of guidelines for workflows for MS based lipidomics
  5. Promote the establishment of guidelines for quantitative lipidomics
  6. Benchmarking and inter-laboratory evaluation of existing software tools for lipid identification
  7. Definition and implementation of reporting standards
  8. Facilitate development, enrichment and curation of lipid databases, ontology, functional annotation for reconstruction of lipid signalling pathways in collaboration with Lipidomics Standards Initiative and LIPID MAPS consortium

WG1 Leader

Justine Bertrand-Michel
National Institute of Cardiovascular and Metabolic Diseases, Toulouse, France

WG1 Vice-leader

Amaury Cazenave-Gassiot

Singapore Lipidomics Incubator (SLING), Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore.

WG1 past Vice-leader

Michal Holčapek
University of Pardubice, Czech Republic